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A cyanobacterial LPS antagonist prevents endotoxin shock and blocks sustained TLR4 stimulation required for cytokine expression
Toll-like receptors (TLRs) function as primary sensors that elicit coordinated innate immune defenses through recognition of microbial products and induction of immune and proinflammatory genes. Here we report the identification and biological characterization of a lipopolysaccharide (LPS)-like mole...
Autores principales: | Macagno, Annalisa, Molteni, Monica, Rinaldi, Andrea, Bertoni, Francesco, Lanzavecchia, Antonio, Rossetti, Carlo, Sallusto, Federica |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118317/ https://www.ncbi.nlm.nih.gov/pubmed/16717116 http://dx.doi.org/10.1084/jem.20060136 |
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