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Bringing order to early B cell chaos

In the early 1990s, Richard (Randy) Hardy and colleagues divided B cell precursors into subpopulations—the Hardy fractions—based on the cells' expression of various cell surface proteins. This classification helped lay the groundwork for our present-day understanding of the molecular events tha...

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Detalles Bibliográficos
Autor principal: Van Epps, Heather L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118322/
https://www.ncbi.nlm.nih.gov/pubmed/16823946
http://dx.doi.org/10.1084/jem.2036fta
Descripción
Sumario:In the early 1990s, Richard (Randy) Hardy and colleagues divided B cell precursors into subpopulations—the Hardy fractions—based on the cells' expression of various cell surface proteins. This classification helped lay the groundwork for our present-day understanding of the molecular events that control early B cell development.