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Igβ tyrosine residues contribute to the control of B cell receptor signaling by regulating receptor internalization

Immunoglobulin (Ig)α and Igβ initiate B cell receptor (BCR) signaling through immune receptor tyrosine activation motifs (ITAMs) that are targets of SH2 domain–containing kinases. To examine the function of Igβ ITAM tyrosine resides in mature B cells in vivo, we exchanged these residues for alanine...

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Detalles Bibliográficos
Autores principales:	Gazumyan, Anna, Reichlin, Amy, Nussenzweig, Michel C.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2006
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118343/ https://www.ncbi.nlm.nih.gov/pubmed/16818674 http://dx.doi.org/10.1084/jem.20060221

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