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Splenectomy inactivates the cholinergic antiinflammatory pathway during lethal endotoxemia and polymicrobial sepsis
The innate immune system protects against infection and tissue injury through the specialized organs of the reticuloendothelial system, including the lungs, liver, and spleen. The central nervous system regulates innate immune responses via the vagus nerve, a mechanism termed the cholinergic antiinf...
Autores principales: | Huston, Jared M., Ochani, Mahendar, Rosas-Ballina, Mauricio, Liao, Hong, Ochani, Kanta, Pavlov, Valentin A., Gallowitsch-Puerta, Margot, Ashok, Mala, Czura, Christopher J., Foxwell, Brian, Tracey, Kevin J., Ulloa, Luis |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118357/ https://www.ncbi.nlm.nih.gov/pubmed/16785311 http://dx.doi.org/10.1084/jem.20052362 |
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