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Protection from lethal septic peritonitis by neutralizing the biological function of interleukin 27
The immune response to bacterial infections must be tightly controlled to guarantee pathogen elimination while preventing tissue damage by uncontrolled inflammation. Here, we demonstrate a key role of interleukin (IL)-27 in regulating this critical balance. IL-27 was rapidly induced during murine ex...
Autores principales: | Wirtz, Stefan, Tubbe, Ingrid, Galle, Peter R., Schild, Hans J., Birkenbach, Mark, Blumberg, Richard S., Neurath, Markus F. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118378/ https://www.ncbi.nlm.nih.gov/pubmed/16880260 http://dx.doi.org/10.1084/jem.20060471 |
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