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Enhancing immunogenicity by limiting susceptibility to lysosomal proteolysis
T cells recognize protein antigens as short peptides processed and displayed by antigen-presenting cells. However, the mechanism of peptide selection is incompletely understood, and, consequently, the differences in the immunogenicity of protein antigens remain largely unpredictable and difficult to...
Autores principales: | Delamarre, Lélia, Couture, Rachael, Mellman, Ira, Trombetta, E. Sergio |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118388/ https://www.ncbi.nlm.nih.gov/pubmed/16908625 http://dx.doi.org/10.1084/jem.20052442 |
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