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Vacuolar and plasma membrane stripping and autophagic elimination of Toxoplasma gondii in primed effector macrophages
Apicomplexan protozoan pathogens avoid destruction and establish a replicative niche within host cells by forming a nonfusogenic parasitophorous vacuole (PV). Here we present evidence for lysosome-mediated degradation of Toxoplasma gondii after invasion of macrophages activated in vivo. Pathogen eli...
Autores principales: | Ling, Yun M., Shaw, Michael H., Ayala, Carol, Coppens, Isabelle, Taylor, Gregory A., Ferguson, David J.P., Yap, George S. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118399/ https://www.ncbi.nlm.nih.gov/pubmed/16940170 http://dx.doi.org/10.1084/jem.20061318 |
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