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The nuclear receptor LRH-1 critically regulates extra-adrenal glucocorticoid synthesis in the intestine

The nuclear receptor liver receptor homologue-1 (LRH-1, NR5A2) is a crucial transcriptional regulator of many metabolic pathways. In addition, LRH-1 is expressed in intestinal crypt cells where it regulates the epithelial cell renewal and contributes to tumorigenesis through the induction of cell cy...

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Detalles Bibliográficos
Autores principales:	Mueller, Matthias, Cima, Igor, Noti, Mario, Fuhrer, Andrea, Jakob, Sabine, Dubuquoy, Laurent, Schoonjans, Kristina, Brunner, Thomas
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2006
Materias:	Brief Definitive Reports
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118403/ https://www.ncbi.nlm.nih.gov/pubmed/16923850 http://dx.doi.org/10.1084/jem.20060357

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