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IFNγ: Issuing macrophages a license to kill
T cells tell macrophages when to start making the toxic soup of lysosomal enzymes, reactive oxygen species, and nitric oxide that destroys intracellular pathogens. In 1983, Carl Nathan proved that this start signal comes in the form of the secreted cytokine IFNγ.
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| Formato: | Texto |
| Lenguaje: | English |
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The Rockefeller University Press
2007
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118418/ https://www.ncbi.nlm.nih.gov/pubmed/17227915 http://dx.doi.org/10.1084/jem.2041fta |
| _version_ | 1782141021432315904 |
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| author | Bashyam, Hema |
| author_facet | Bashyam, Hema |
| author_sort | Bashyam, Hema |
| collection | PubMed |
| description | T cells tell macrophages when to start making the toxic soup of lysosomal enzymes, reactive oxygen species, and nitric oxide that destroys intracellular pathogens. In 1983, Carl Nathan proved that this start signal comes in the form of the secreted cytokine IFNγ. |
| format | Text |
| id | pubmed-2118418 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2007 |
| publisher | The Rockefeller University Press |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-21184182007-12-13 IFNγ: Issuing macrophages a license to kill Bashyam, Hema J Exp Med From the Archive T cells tell macrophages when to start making the toxic soup of lysosomal enzymes, reactive oxygen species, and nitric oxide that destroys intracellular pathogens. In 1983, Carl Nathan proved that this start signal comes in the form of the secreted cytokine IFNγ. The Rockefeller University Press 2007-01-22 /pmc/articles/PMC2118418/ /pubmed/17227915 http://dx.doi.org/10.1084/jem.2041fta Text en Copyright © 2007, The Rockefeller University Press This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/). |
| spellingShingle | From the Archive Bashyam, Hema IFNγ: Issuing macrophages a license to kill |
| title | IFNγ: Issuing macrophages a license to kill |
| title_full | IFNγ: Issuing macrophages a license to kill |
| title_fullStr | IFNγ: Issuing macrophages a license to kill |
| title_full_unstemmed | IFNγ: Issuing macrophages a license to kill |
| title_short | IFNγ: Issuing macrophages a license to kill |
| title_sort | ifnγ: issuing macrophages a license to kill |
| topic | From the Archive |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118418/ https://www.ncbi.nlm.nih.gov/pubmed/17227915 http://dx.doi.org/10.1084/jem.2041fta |
| work_keys_str_mv | AT bashyamhema ifngissuingmacrophagesalicensetokill |