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Anti–TNF-α therapy induces a distinct regulatory T cell population in patients with rheumatoid arthritis via TGF-β

The induction of regulatory T (T reg) cells holds considerable potential as a treatment for autoimmune diseases. We have previously shown that CD4(+)CD25(hi) T reg cells isolated from patients with active rheumatoid arthritis (RA) have a defect in their ability to suppress proinflammatory cytokine p...

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Detalles Bibliográficos
Autores principales:	Nadkarni, Suchita, Mauri, Claudia, Ehrenstein, Michael R.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2007
Materias:	Brief Definitive Reports
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118431/ https://www.ncbi.nlm.nih.gov/pubmed/17200409 http://dx.doi.org/10.1084/jem.20061531

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