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Class A scavenger receptors regulate tolerance against apoptotic cells, and autoantibodies against these receptors are predictive of systemic lupus
Apoptotic cells are considered to be a major source for autoantigens in autoimmune diseases such as systemic lupus erythematosus (SLE). In agreement with this, defective clearance of apoptotic cells has been shown to increase disease susceptibility. Still, little is known about how apoptotic cell–de...
Autores principales: | Wermeling, Fredrik, Chen, Yunying, Pikkarainen, Timo, Scheynius, Annika, Winqvist, Ola, Izui, Shozo, Ravetch, Jeffrey V., Tryggvason, Karl, Karlsson, Mikael C.I. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118440/ https://www.ncbi.nlm.nih.gov/pubmed/17893199 http://dx.doi.org/10.1084/jem.20070600 |
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