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Chromosomal reinsertion of broken RSS ends during T cell development

The V(D)J recombinase catalyzes DNA transposition and translocation both in vitro and in vivo. Because lymphoid malignancies contain chromosomal translocations involving antigen receptor and protooncogene loci, it is critical to understand the types of “mistakes” made by the recombinase. Using a new...

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Detalles Bibliográficos
Autores principales:	Curry, John D., Schulz, Danae, Guidos, Cynthia J., Danska, Jayne S., Nutter, Lauryl, Nussenzweig, Andre, Schlissel, Mark S.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2007
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118463/ https://www.ncbi.nlm.nih.gov/pubmed/17785508 http://dx.doi.org/10.1084/jem.20070583

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