Superior control of HIV-1 replication by CD8(+) T cells is reflected by their avidity, polyfunctionality, and clonal turnover

The key attributes of CD8(+) T cell protective immunity in human immunodeficiency virus (HIV) infection remain unclear. We report that CD8(+) T cell responses specific for Gag and, in particular, the immunodominant p24 epitope KK10 correlate with control of HIV-1 replication in human histocompatibil...

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Detalles Bibliográficos
Autores principales: Almeida, Jorge R., Price, David A., Papagno, Laura, Arkoub, Zaïna Aït, Sauce, Delphine, Bornstein, Ethan, Asher, Tedi E., Samri, Assia, Schnuriger, Aurélie, Theodorou, Ioannis, Costagliola, Dominique, Rouzioux, Christine, Agut, Henri, Marcelin, Anne-Geneviève, Douek, Daniel, Autran, Brigitte, Appay, Victor
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118466/
https://www.ncbi.nlm.nih.gov/pubmed/17893201
http://dx.doi.org/10.1084/jem.20070784

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118466/
https://www.ncbi.nlm.nih.gov/pubmed/17893201
http://dx.doi.org/10.1084/jem.20070784

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