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Myosin IIA is required for cytolytic granule exocytosis in human NK cells

Natural killer (NK) cell cytotoxicity involves the formation of an activating immunological synapse (IS) between the effector and target cell through which granzymes and perforin contained in lytic granules are delivered to the target cell via exocytosis. Inhibition of nonmuscle myosin II in human N...

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Detalles Bibliográficos
Autores principales:	Andzelm, Milena M., Chen, Xi, Krzewski, Konrad, Orange, Jordan S., Strominger, Jack L.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2007
Materias:	Brief Definitive Reports
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118468/ https://www.ncbi.nlm.nih.gov/pubmed/17875677 http://dx.doi.org/10.1084/jem.20071143

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