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Proliferative arrest and rapid turnover of thymic epithelial cells expressing Aire

Expression of autoimmune regulator (Aire) by thymic medullary epithelial cells (MECs) is critical for central tolerance of self. To explore the mechanism by which such a rare cell population imposes tolerance on the large repertoire of differentiating thymocytes, we examined the proliferation and tu...

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Detalles Bibliográficos
Autores principales:	Gray, Daniel, Abramson, Jakub, Benoist, Christophe, Mathis, Diane
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2007
Materias:	Brief Definitive Reports
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118482/ https://www.ncbi.nlm.nih.gov/pubmed/17908938 http://dx.doi.org/10.1084/jem.20070795

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