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Germinal centers in human lymph nodes contain reactivated memory B cells

To reveal migration trails of antigen-responsive B cells in lymphoid tissue, we analyzed immunoglobulin (Ig)M-V(H) and IgG-V(H) transcripts of germinal center (GC) samples microdissected from three reactive human lymph nodes. Single B cell clones were found in multiple GCs, one clone even in as many...

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Detalles Bibliográficos
Autores principales:	Bende, Richard J., van Maldegem, Febe, Triesscheijn, Martijn, Wormhoudt, Thera A.M., Guijt, Richard, van Noesel, Carel J.M.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2007
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118493/ https://www.ncbi.nlm.nih.gov/pubmed/17938234 http://dx.doi.org/10.1084/jem.20071006

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