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Thymic emigration revisited

Conventional αβ T cell precursors undergo positive selection in the thymic cortex. When this is successful, they migrate to the medulla and are exposed to tissue-specific antigens (TSA) for purposes of central tolerance, and they undergo maturation to become functionally responsive T cells. It is co...

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Detalles Bibliográficos
Autores principales:	McCaughtry, Tom M., Wilken, Matthew S., Hogquist, Kristin A.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2007
Materias:	Brief Definitive Reports
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118501/ https://www.ncbi.nlm.nih.gov/pubmed/17908937 http://dx.doi.org/10.1084/jem.20070601

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