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A viral CTL escape mutation leading to immunoglobulin-like transcript 4–mediated functional inhibition of myelomonocytic cells

Viral mutational escape can reduce or abrogate recognition by the T cell receptor (TCR) of virus-specific CD8(+) T cells. However, very little is known about the impact of cytotoxic T lymphocyte (CTL) epitope mutations on interactions between peptide–major histocompatibility complex (MHC) class I co...

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Detalles Bibliográficos
Autores principales: Lichterfeld, Mathias, Kavanagh, Daniel G., Williams, Katie L., Moza, Beenu, Mui, Stanley K., Miura, ToshiYuki, Sivamurthy, Rohini, Allgaier, Rachel, Pereyra, Florencia, Trocha, Alicja, Feeney, Margaret, Gandhi, Rajesh T., Rosenberg, Eric S., Altfeld, Marcus, Allen, Todd M., Allen, Rachel, Walker, Bruce D., Sundberg, Eric J., Yu, Xu G.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118510/
https://www.ncbi.nlm.nih.gov/pubmed/18025130
http://dx.doi.org/10.1084/jem.20061865