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A viral CTL escape mutation leading to immunoglobulin-like transcript 4–mediated functional inhibition of myelomonocytic cells
Viral mutational escape can reduce or abrogate recognition by the T cell receptor (TCR) of virus-specific CD8(+) T cells. However, very little is known about the impact of cytotoxic T lymphocyte (CTL) epitope mutations on interactions between peptide–major histocompatibility complex (MHC) class I co...
Autores principales: | , , , , , , , , , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118510/ https://www.ncbi.nlm.nih.gov/pubmed/18025130 http://dx.doi.org/10.1084/jem.20061865 |