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A viral CTL escape mutation leading to immunoglobulin-like transcript 4–mediated functional inhibition of myelomonocytic cells
Viral mutational escape can reduce or abrogate recognition by the T cell receptor (TCR) of virus-specific CD8(+) T cells. However, very little is known about the impact of cytotoxic T lymphocyte (CTL) epitope mutations on interactions between peptide–major histocompatibility complex (MHC) class I co...
Autores principales: | Lichterfeld, Mathias, Kavanagh, Daniel G., Williams, Katie L., Moza, Beenu, Mui, Stanley K., Miura, ToshiYuki, Sivamurthy, Rohini, Allgaier, Rachel, Pereyra, Florencia, Trocha, Alicja, Feeney, Margaret, Gandhi, Rajesh T., Rosenberg, Eric S., Altfeld, Marcus, Allen, Todd M., Allen, Rachel, Walker, Bruce D., Sundberg, Eric J., Yu, Xu G. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118510/ https://www.ncbi.nlm.nih.gov/pubmed/18025130 http://dx.doi.org/10.1084/jem.20061865 |
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