Reduced receptor editing in lupus-prone MRL/lpr mice

The initial B cell repertoire contains a considerable proportion of autoreactive specificities. The first major B cell tolerance checkpoint is at the stage of the immature B cell, where receptor editing is the primary mode of eliminating self-reactivity. The cells that emigrate from the bone marrow...

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Detalles Bibliográficos
Autores principales: Lamoureux, Jennifer L., Watson, Lisa C., Cherrier, Marie, Skog, Patrick, Nemazee, David, Feeney, Ann J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118512/
https://www.ncbi.nlm.nih.gov/pubmed/17967905
http://dx.doi.org/10.1084/jem.20071268

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118512/
https://www.ncbi.nlm.nih.gov/pubmed/17967905
http://dx.doi.org/10.1084/jem.20071268

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