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Viral antigen and extensive division maintain virus-specific CD8 T cells during chronic infection

Efficient maintenance of memory CD8 T cells is central to long-term protective immunity. IL-7– and IL-15–driven homeostatic proliferation is essential for long-term memory CD8 T cell persistence after acute infections. During chronic infections, however, virus-specific CD8 T cells respond poorly to...

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Detalles Bibliográficos
Autores principales:	Shin, Haina, Blackburn, Shawn D., Blattman, Joseph N., Wherry, E. John
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2007
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118542/ https://www.ncbi.nlm.nih.gov/pubmed/17420267 http://dx.doi.org/10.1084/jem.20061937

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