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Thromboxane A(2) is a key regulator of pathogenesis during Trypanosoma cruzi infection

Chagas' disease is caused by infection with the parasite Trypanosoma cruzi. We report that infected, but not uninfected, human endothelial cells (ECs) released thromboxane A(2) (TXA(2)). Physical chromatography and liquid chromatography-tandem mass spectrometry revealed that TXA(2) is the predo...

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Detalles Bibliográficos
Autores principales: Ashton, Anthony W., Mukherjee, Shankar, Nagajyothi, FNU, Huang, Huan, Braunstein, Vicki L., Desruisseaux, Mahalia S., Factor, Stephen M., Lopez, Lillie, Berman, Joan W., Wittner, Murray, Scherer, Philipp E., Capra, Valerie, Coffman, Thomas M., Serhan, Charles N., Gotlinger, Katherine, Wu, Kenneth K., Weiss, Louis M., Tanowitz, Herbert B.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118547/
https://www.ncbi.nlm.nih.gov/pubmed/17420269
http://dx.doi.org/10.1084/jem.20062432