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Splenic accumulation of IL-10 mRNA in T cells distinct from CD4(+)CD25(+) (Foxp3) regulatory T cells in human visceral leishmaniasis
Visceral leishmaniasis (VL) is a life-threatening disease characterized by uncontrolled parasitization of the spleen, liver, and bone marrow. Interleukin (IL)-10 has been implicated in the suppression of host immunity in human VL based on the elevated levels of IL-10 observed in plasma and lesional...
Autores principales: | Nylén, Susanne, Maurya, Radheshyam, Eidsmo, Liv, Manandhar, Krishna Das, Sundar, Shyam, Sacks, David |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118563/ https://www.ncbi.nlm.nih.gov/pubmed/17389235 http://dx.doi.org/10.1084/jem.20061141 |
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