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Regulation of AID expression in the immune response
The B cell–specific enzyme activation-induced cytidine deaminase (AID) has been shown to be essential for isotype switching and affinity maturation of antibody genes during the immune response. Conversely, AID activity has also been linked to autoimmunity and tumorigenesis. Determining how AID expre...
Autores principales: | Crouch, Elizabeth E., Li, Zhiyu, Takizawa, Makiko, Fichtner-Feigl, Stefan, Gourzi, Polyxeni, Montaño, Carolina, Feigenbaum, Lionel, Wilson, Patrick, Janz, Siegfried, Papavasiliou, F. Nina, Casellas, Rafael |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118564/ https://www.ncbi.nlm.nih.gov/pubmed/17452520 http://dx.doi.org/10.1084/jem.20061952 |
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