Lysosomal integral membrane protein 2 is a novel component of the cardiac intercalated disc and vital for load-induced cardiac myocyte hypertrophy

The intercalated disc (ID) of cardiac myocytes is emerging as a crucial structure in the heart. Loss of ID proteins like N-cadherin causes lethal cardiac abnormalities, and mutations in ID proteins cause human cardiomyopathy. A comprehensive screen for novel mechanisms in failing hearts demonstrated...

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Detalles Bibliográficos
Autores principales: Schroen, Blanche, Leenders, Joost J., van Erk, Arie, Bertrand, Anne T., van Loon, Mirjam, van Leeuwen, Rick E., Kubben, Nard, Duisters, Rudy F., Schellings, Mark W., Janssen, Ben J., Debets, Jacques J., Schwake, Michael, Høydal, Morten A., Heymans, Stephane, Saftig, Paul, Pinto, Yigal M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118572/
https://www.ncbi.nlm.nih.gov/pubmed/17485520
http://dx.doi.org/10.1084/jem.20070145

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