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Type I interferon signaling is required for activation of the inflammasome during Francisella infection

Francisella tularensis is a pathogenic bacterium whose virulence is linked to its ability to replicate within the host cell cytosol. Entry into the macrophage cytosol activates a host-protective multimolecular complex called the inflammasome to release the proinflammatory cytokines interleukin (IL)-...

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Detalles Bibliográficos
Autores principales:	Henry, Thomas, Brotcke, Anna, Weiss, David S., Thompson, Lucinda J., Monack, Denise M.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2007
Materias:	Brief Definitive Reports
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118578/ https://www.ncbi.nlm.nih.gov/pubmed/17452523 http://dx.doi.org/10.1084/jem.20062665

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