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Interleukin-12: A master regulator
Early resistance to pathogens requires a swift response from NK cells. In 1989, Giorgio Trinchieri identified an NK growth factor and activator, later called interleukin-12 (IL-12). This discovery helped reveal the regulatory link between innate and adaptive immunity.
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Formato: | Texto |
Lenguaje: | English |
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The Rockefeller University Press
2007
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118588/ https://www.ncbi.nlm.nih.gov/pubmed/17485522 http://dx.doi.org/10.1084/jem.2045fta |
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author | Bashyam, Hema |
author_facet | Bashyam, Hema |
author_sort | Bashyam, Hema |
collection | PubMed |
description | Early resistance to pathogens requires a swift response from NK cells. In 1989, Giorgio Trinchieri identified an NK growth factor and activator, later called interleukin-12 (IL-12). This discovery helped reveal the regulatory link between innate and adaptive immunity. |
format | Text |
id | pubmed-2118588 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2007 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-21185882007-12-13 Interleukin-12: A master regulator Bashyam, Hema J Exp Med From the Archive Early resistance to pathogens requires a swift response from NK cells. In 1989, Giorgio Trinchieri identified an NK growth factor and activator, later called interleukin-12 (IL-12). This discovery helped reveal the regulatory link between innate and adaptive immunity. The Rockefeller University Press 2007-05-14 /pmc/articles/PMC2118588/ /pubmed/17485522 http://dx.doi.org/10.1084/jem.2045fta Text en Copyright © 2007, The Rockefeller University Press This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | From the Archive Bashyam, Hema Interleukin-12: A master regulator |
title | Interleukin-12: A master regulator |
title_full | Interleukin-12: A master regulator |
title_fullStr | Interleukin-12: A master regulator |
title_full_unstemmed | Interleukin-12: A master regulator |
title_short | Interleukin-12: A master regulator |
title_sort | interleukin-12: a master regulator |
topic | From the Archive |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118588/ https://www.ncbi.nlm.nih.gov/pubmed/17485522 http://dx.doi.org/10.1084/jem.2045fta |
work_keys_str_mv | AT bashyamhema interleukin12amasterregulator |