Distinct domains in Nbs1 regulate irradiation-induced checkpoints and apoptosis

The chromosomal instability syndromes Nijmegen breakage syndrome (NBS) and ataxia telangiectasia (AT) share many overlapping phenotypes, including cancer predisposition, radiation sensitivity, cell-cycle checkpoint defects, immunodeficiency, and gonadal dysfunction. The NBS protein Nbs1 is not only...

Descripción completa

Detalles Bibliográficos
Autores principales: Difilippantonio, Simone, Celeste, Arkady, Kruhlak, Michael J., Lee, Youngsoo, Difilippantonio, Michael J., Feigenbaum, Lionel, Jackson, Stephen P., McKinnon, Peter J., Nussenzweig, André
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Brief Definitive Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118591/
https://www.ncbi.nlm.nih.gov/pubmed/17485521
http://dx.doi.org/10.1084/jem.20070319

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118591/
https://www.ncbi.nlm.nih.gov/pubmed/17485521
http://dx.doi.org/10.1084/jem.20070319

Ejemplares similares