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CD8 single-cell gene coexpression reveals three different effector types present at distinct phases of the immune response
To study in vivo CD8 T cell differentiation, we quantified the coexpression of multiple genes in single cells throughout immune responses. After in vitro activation, CD8 T cells rapidly express effector molecules and cease their expression when the antigen is removed. Gene behavior after in vivo act...
Autores principales: | Peixoto, António, Evaristo, César, Munitic, Ivana, Monteiro, Marta, Charbit, Alain, Rocha, Benedita, Veiga-Fernandes, Henrique |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118592/ https://www.ncbi.nlm.nih.gov/pubmed/17485515 http://dx.doi.org/10.1084/jem.20062349 |
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