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CD8 single-cell gene coexpression reveals three different effector types present at distinct phases of the immune response

To study in vivo CD8 T cell differentiation, we quantified the coexpression of multiple genes in single cells throughout immune responses. After in vitro activation, CD8 T cells rapidly express effector molecules and cease their expression when the antigen is removed. Gene behavior after in vivo act...

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Detalles Bibliográficos
Autores principales: Peixoto, António, Evaristo, César, Munitic, Ivana, Monteiro, Marta, Charbit, Alain, Rocha, Benedita, Veiga-Fernandes, Henrique
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118592/
https://www.ncbi.nlm.nih.gov/pubmed/17485515
http://dx.doi.org/10.1084/jem.20062349

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