A novel inhibitor of the alternative pathway of complement reverses inflammation and bone destruction in experimental arthritis

Complement is an important component of the innate and adaptive immune response, yet complement split products generated through activation of each of the three complement pathways (classical, alternative, and lectin) can cause inflammation and tissue destruction. Previous studies have shown that co...

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Detalles Bibliográficos
Autores principales: Katschke, Kenneth J., Helmy, Karim Y., Steffek, Micah, Xi, Hongkang, Yin, JianPing, Lee, Wyne P., Gribling, Peter, Barck, Kai H., Carano, Richard A.D., Taylor, Robin E., Rangell, Linda, Diehl, Lauri, Hass, Philip E., Wiesmann, Christian, van Lookeren Campagne, Menno
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Brief Definitive Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118595/
https://www.ncbi.nlm.nih.gov/pubmed/17548523
http://dx.doi.org/10.1084/jem.20070432

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