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Selective suppression of dendritic cell functions by Mycobacterium ulcerans toxin mycolactone

Mycolactone is a polyketide toxin produced by Mycobacterium ulcerans (Mu), the causative agent of the skin disease Buruli ulcer (BU). Surprisingly, infected tissues lack inflammatory infiltrates. Structural similarities between mycolactone and immunosuppressive agents led us to investigate the immun...

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Detalles Bibliográficos
Autores principales: Coutanceau, Emmanuelle, Decalf, Jeremie, Martino, Angelo, Babon, Aurélie, Winter, Nathalie, Cole, Stewart T., Albert, Matthew L., Demangel, Caroline
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118602/
https://www.ncbi.nlm.nih.gov/pubmed/17517970
http://dx.doi.org/10.1084/jem.20070234