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Selective suppression of dendritic cell functions by Mycobacterium ulcerans toxin mycolactone
Mycolactone is a polyketide toxin produced by Mycobacterium ulcerans (Mu), the causative agent of the skin disease Buruli ulcer (BU). Surprisingly, infected tissues lack inflammatory infiltrates. Structural similarities between mycolactone and immunosuppressive agents led us to investigate the immun...
Autores principales: | Coutanceau, Emmanuelle, Decalf, Jeremie, Martino, Angelo, Babon, Aurélie, Winter, Nathalie, Cole, Stewart T., Albert, Matthew L., Demangel, Caroline |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118602/ https://www.ncbi.nlm.nih.gov/pubmed/17517970 http://dx.doi.org/10.1084/jem.20070234 |
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