Deubiquitinating enzyme CYLD negatively regulates the ubiquitin-dependent kinase Tak1 and prevents abnormal T cell responses

The deubiquitinating enzyme CYLD has recently been implicated in the regulation of signal transduction, but its physiological function and mechanism of action are still elusive. In this study, we show that CYLD plays a pivotal role in regulating T cell activation and homeostasis. T cells derived fro...

Descripción completa

Detalles Bibliográficos
Autores principales: Reiley, William W., Jin, Wei, Lee, Andrew Joon, Wright, Ato, Wu, Xuefeng, Tewalt, Eric F., Leonard, Timothy O., Norbury, Christopher C., Fitzpatrick, Leo, Zhang, Minying, Sun, Shao-Cong
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118606/
https://www.ncbi.nlm.nih.gov/pubmed/17548520
http://dx.doi.org/10.1084/jem.20062694

Ejemplares similares

Ejemplares similares