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Immunization with vaccinia virus induces polyfunctional and phenotypically distinctive CD8(+) T cell responses

Vaccinia virus immunization provides lifelong protection against smallpox, but the mechanisms of this exquisite protection are unknown. We used polychromatic flow cytometry to characterize the functional and phenotypic profile of CD8(+) T cells induced by vaccinia virus immunization in a comparative...

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Detalles Bibliográficos
Autores principales: Precopio, Melissa L., Betts, Michael R., Parrino, Janie, Price, David A., Gostick, Emma, Ambrozak, David R., Asher, Tedi E., Douek, Daniel C., Harari, Alexandre, Pantaleo, Giuseppe, Bailer, Robert, Graham, Barney S., Roederer, Mario, Koup, Richard A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118607/
https://www.ncbi.nlm.nih.gov/pubmed/17535971
http://dx.doi.org/10.1084/jem.20062363

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