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Immunization with vaccinia virus induces polyfunctional and phenotypically distinctive CD8(+) T cell responses
Vaccinia virus immunization provides lifelong protection against smallpox, but the mechanisms of this exquisite protection are unknown. We used polychromatic flow cytometry to characterize the functional and phenotypic profile of CD8(+) T cells induced by vaccinia virus immunization in a comparative...
Autores principales: | Precopio, Melissa L., Betts, Michael R., Parrino, Janie, Price, David A., Gostick, Emma, Ambrozak, David R., Asher, Tedi E., Douek, Daniel C., Harari, Alexandre, Pantaleo, Giuseppe, Bailer, Robert, Graham, Barney S., Roederer, Mario, Koup, Richard A. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118607/ https://www.ncbi.nlm.nih.gov/pubmed/17535971 http://dx.doi.org/10.1084/jem.20062363 |
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