Tumor suppressor p53 Arg72Pro polymorphism and longevity, cancer survival, and risk of cancer in the general population

p53 is an important tumor suppressor, normally preventing cancer development via apoptosis. A genomic Arg72Pro substitution in the p53 protein has important influence on cell death via apoptosis, which could be beneficial. We therefore tested the hypotheses that this polymorphism influences longevit...

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Detalles Bibliográficos
Autores principales: Ørsted, David Dynnes, Bojesen, Stig Egil, Tybjærg-Hansen, Anne, Nordestgaard, Børge Grønne
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Brief Definitive Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118619/
https://www.ncbi.nlm.nih.gov/pubmed/17535973
http://dx.doi.org/10.1084/jem.20062476

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118619/
https://www.ncbi.nlm.nih.gov/pubmed/17535973
http://dx.doi.org/10.1084/jem.20062476

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