Cargando…

Tumor suppressor p53 Arg72Pro polymorphism and longevity, cancer survival, and risk of cancer in the general population

p53 is an important tumor suppressor, normally preventing cancer development via apoptosis. A genomic Arg72Pro substitution in the p53 protein has important influence on cell death via apoptosis, which could be beneficial. We therefore tested the hypotheses that this polymorphism influences longevit...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ørsted, David Dynnes, Bojesen, Stig Egil, Tybjærg-Hansen, Anne, Nordestgaard, Børge Grønne
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2007
Materias:	Brief Definitive Reports
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118619/ https://www.ncbi.nlm.nih.gov/pubmed/17535973 http://dx.doi.org/10.1084/jem.20062476

Ejemplares similares

TP53 Arg72Pro, mortality after cancer, and all-cause mortality in 105,200 individuals
por: Kodal, Jakob B., et al.
Publicado: (2017)

The human Tp53 Arg72Pro polymorphism explains different functional prognosis in stroke
por: Gomez-Sanchez, Jose C., et al.
Publicado: (2011)

Low high-density lipoprotein and increased risk of several cancers: 2 population-based cohort studies including 116,728 individuals
por: Pedersen, Kasper Mønsted, et al.
Publicado: (2020)

Lymphopenia and risk of infection and infection-related death in 98,344 individuals from a prospective Danish population-based study
por: Warny, Marie, et al.
Publicado: (2018)

Tocilizumab and soluble interleukin-6 receptor in JAK2V617F somatic mutation and myeloproliferative neoplasm
por: Pedersen, Kasper Mønsted, et al.
Publicado: (2020)

Two-fold risk of pneumonia and respiratory mortality in individuals with myeloproliferative neoplasm: A population-based cohort study
por: Pedersen, Kasper Mønsted, et al.
Publicado: (2020)

Loss-of-function polymorphism in IL6R reduces risk of JAK2V617F somatic mutation and myeloproliferative neoplasm: A Mendelian randomization study
por: Pedersen, Kasper Mønsted, et al.
Publicado: (2020)

No association of breast cancer risk with integrin beta(3) (ITGB3) Leu33Pro genotype
por: Bojesen, S E, et al.
Publicado: (2005)

Genetic variants in the adenosine triphosphate-binding cassette transporter A1 and risk of age-related macular degeneration
por: Nordestgaard, Liv Tybjærg, et al.
Publicado: (2023)

The Neuronal Ischemic Tolerance Is Conditioned by the Tp53 Arg72Pro Polymorphism
por: Ramos-Araque, Maria E., et al.
Publicado: (2018)

Arg72Pro Polymorphism of TP53 Gene and the Risk of Skin Cancer: a Meta-Analysis
por: Ye, Jun, et al.
Publicado: (2013)

Impact of p53 arg72pro SNP on Breast Cancer Risk in North Indian Population
por: Akhter, Naseem, et al.
Publicado: (2018)

Studies of the Association of Arg72Pro of Tumor Suppressor Protein p53 with Type 2 Diabetes in a Combined Analysis of 55,521 Europeans
por: Burgdorf, Kristoffer Sølvsten, et al.
Publicado: (2011)

Increased Risk of Cutaneous Melanoma Associated with p53 Arg72Pro Polymorphism
por: Geng, Peiliang, et al.
Publicado: (2015)

S280: INDIVIDUALS WITH HFE C282Y HOMOZYGOSITY AND DIABETES HAVE ALMOST TWO-FOLD RISK OF DEATH COMPARED TO NON-CARRIERS WITH DIABETES: A PROSPECTIVE STUDY OF A 132,542-INDIVIDUAL GENERAL POPULATION COHORT
por: Mottelson, Mathis, et al.
Publicado: (2023)

Both p53 codon 72 Arg/Arg and pro/Arg genotypes in glioblastoma multiforme are associated with a better prognosis in bevacizumab treatment
por: Shen, Chiung-Chyi, et al.
Publicado: (2020)

Association between p53 Pro72Arg polymorphism and prostate cancer risk: a meta-analysis
por: Zhang, Lifeng, et al.
Publicado: (2011)

Association of MDM2 SNP309 and TP53 Arg72Pro polymorphisms with risk of endometrial cancer
por: YONEDA, TOMOKO, et al.
Publicado: (2013)

P53 codon 72 Arg/Pro polymorphism and lung cancer risk in Asians: an updated meta-analysis
por: Wang, Siyang, et al.
Publicado: (2013)

Association of p53 codon 72 polymorphism with advanced lung cancer: the Arg allele is preferentially retained in tumours arising in Arg/Pro germline heterozygotes
por: Papadakis, E D, et al.
Publicado: (2002)

No association between TP53 Arg72Pro polymorphism and ovarian cancer risk: evidence from 10113 subjects
por: Zhang, Anqi, et al.
Publicado: (2017)

Association between p53 Codon 72 (Arg72Pro) Polymorphism and Primary Open-Angle Glaucoma in Iranian Patients
por: Neamatzadeh, Hossein, et al.
Publicado: (2015)

Evaluating the Association between p53 Codon 72 Arg>Pro Polymorphism and Risk of Ovary Cancer: A Meta-Analysis
por: Alqumber, Mohammed A. A., et al.
Publicado: (2014)

The association between the TP53 Arg72Pro polymorphism and colorectal cancer: An updated meta-analysis based on 32 studies
por: Tian, Xin, et al.
Publicado: (2016)

p.Arg72Pro polymorphism of P53 and breast cancer risk: a meta-analysis of case-control studies
por: Diakite, Brehima, et al.
Publicado: (2020)

TP53 Arg72Pro and XPD Lys751Gln Gene Polymorphisms and Risk of Lung Cancer in Bangladeshi Patients
por: Nairuz, Tahsin, et al.
Publicado: (2020)

Secular trends in smoking in relation to prevalent and incident smoking-related disease: A prospective population-based study
por: Tonnesen, Philip, et al.
Publicado: (2019)

Association of p53 codon 72 Arg>Pro polymorphism and risk of cancer in Iranian population: A systematic review and meta-analysis
por: Roshani, Daem, et al.
Publicado: (2017)

Association of XRCC1 Arg399GIn and Tp53 Arg72Pro polymorphisms and increased risk of uterine leiomyoma - A case-control study
por: Yaghmaei, Minoo, et al.
Publicado: (2015)

Neovascularization and functional recovery after intracerebral hemorrhage is conditioned by the Tp53 Arg72Pro single-nucleotide polymorphism
por: Rodríguez, Cristina, et al.
Publicado: (2017)

Association between TP53 gene Arg72Pro polymorphism and Wilms’ tumor risk in a Chinese population
por: Fu, Wen, et al.
Publicado: (2017)

Association Between Arg72Pro Polymorphism in TP53 and Malignant Abdominal Solid Tumor Risk in Hunan Children
por: Liu, Zan, et al.
Publicado: (2021)

Association of TP53 Codon 72 Arg>Pro Polymorphism with Breast and Lung Cancer Risk in the South Asian Population: A Meta-Analysis
por: Jafrin, Sarah, et al.
Publicado: (2020)

p53 Arg72Pro polymorphism, adiposity status, and cancer risk: Two case‐cohorts within a Japanese prospective study
por: Nakano, Shiori, et al.
Publicado: (2022)

The association of polymorphic markers Arg399Gln of XRCC1 gene, Arg72Pro of TP53 gene and T309G of MDM2 gene with breast cancer in Kyrgyz females
por: Isakova, Jainagul, et al.
Publicado: (2017)

p53: Pro-aging or pro-longevity?
por: de Keizer*, Peter L.J., et al.
Publicado: (2010)

TP53Gene Pro72Arg(rs1042522) Single Nucleotide Polymorphism as Not a Risk Factor for Colorectal Cancer in the Iranian Azari Population
por: Asadi, Milad, et al.
Publicado: (2017)

Contribution of retinoblastoma LOH and the p53 Arg/Pro polymorphism to cervical cancer
por: ELTAHIR, HUDA A., et al.
Publicado: (2012)

An evaluation of the polymorphisms Ins16bp and Arg72Pro in p53 as breast cancer risk modifiers in BRCA1 and BRCA2 mutation carriers
por: Osorio, A, et al.
Publicado: (2008)

The TP53 Arg72Pro and MDM2 309G>T polymorphisms are not associated with breast cancer risk in BRCA1 and BRCA2 mutation carriers
por: Sinilnikova, O M, et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_ht2ts9l8969g4k13dqlc6si1hd