Cargando…
Distinct roles for Syk and ZAP-70 during early thymocyte development
The spleen tyrosine kinase (Syk) and ζ-associated protein of 70 kD (ZAP-70) tyrosine kinases are both expressed during early thymocyte development, but their unique thymic functions have remained obscure. No specific role for Syk during β-selection has been established, and no role has been describe...
Autores principales: | Palacios, Emil H., Weiss, Arthur |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2007
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118636/ https://www.ncbi.nlm.nih.gov/pubmed/17606633 http://dx.doi.org/10.1084/jem.20070405 |
Ejemplares similares
-
Lck promotes Zap70-dependent LAT phosphorylation by bridging Zap70 to LAT
por: Lo, Wan-Lin, et al.
Publicado: (2018) -
Differences in the dynamics of the tandem‐SH2 modules of the Syk and ZAP‐70 tyrosine kinases
por: Hobbs, Helen T., et al.
Publicado: (2021) -
Distinct structural and catalytic roles for Zap70 in formation of the immunological synapse in CTL
por: Jenkins, Misty R, et al.
Publicado: (2014) -
Lck regulates the tyrosine phosphorylation of the T cell receptor subunits and ZAP-70 in murine thymocytes
Publicado: (1996) -
Absence of ZAP-70 prevents signaling through the antigen receptor on peripheral blood T cells but not on thymocytes
Publicado: (1995)