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An intense form of homeostatic proliferation of naive CD8(+) cells driven by IL-2
In conditions of T lymphopenia, interleukin (IL) 7 levels rise and, via T cell receptor for antigen–self–major histocompatibility complex (MHC) interaction, induce residual naive T cells to proliferate. This pattern of lymphopenia-induced “homeostatic” proliferation is typically quite slow and cause...
Autores principales: | Cho, Jae-Ho, Boyman, Onur, Kim, Hee-Ok, Hahm, Bumsuk, Rubinstein, Mark P., Ramsey, Chris, Kim, David M., Surh, Charles D., Sprent, Jonathan |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118670/ https://www.ncbi.nlm.nih.gov/pubmed/17664294 http://dx.doi.org/10.1084/jem.20070740 |
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