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An intense form of homeostatic proliferation of naive CD8(+) cells driven by IL-2

In conditions of T lymphopenia, interleukin (IL) 7 levels rise and, via T cell receptor for antigen–self–major histocompatibility complex (MHC) interaction, induce residual naive T cells to proliferate. This pattern of lymphopenia-induced “homeostatic” proliferation is typically quite slow and cause...

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Detalles Bibliográficos
Autores principales: Cho, Jae-Ho, Boyman, Onur, Kim, Hee-Ok, Hahm, Bumsuk, Rubinstein, Mark P., Ramsey, Chris, Kim, David M., Surh, Charles D., Sprent, Jonathan
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118670/
https://www.ncbi.nlm.nih.gov/pubmed/17664294
http://dx.doi.org/10.1084/jem.20070740

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