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A functionally specialized population of mucosal CD103(+) DCs induces Foxp3(+) regulatory T cells via a TGF-β– and retinoic acid–dependent mechanism
Foxp3(+) regulatory T (T reg) cells play a key role in controlling immune pathological re actions. Many develop their regulatory activity in the thymus, but there is also evidence for development of Foxp3(+) T reg cells from naive precursors in the periphery. Recent studies have shown that transform...
Autores principales: | Coombes, Janine L., Siddiqui, Karima R.R., Arancibia-Cárcamo, Carolina V., Hall, Jason, Sun, Cheng-Ming, Belkaid, Yasmine, Powrie, Fiona |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118683/ https://www.ncbi.nlm.nih.gov/pubmed/17620361 http://dx.doi.org/10.1084/jem.20070590 |
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