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Repression of interleukin-4 in T helper type 1 cells by Runx/Cbfβ binding to the Il4 silencer
Interferon γ (IFNγ) is the hallmark cytokine produced by T helper type 1 (Th1) cells, whereas interleukin (IL)-4 is the hallmark cytokine produced by Th2 cells. Although previous studies have revealed the roles of cytokine signaling and of transcription factors during differentiation of Th1 or Th2 c...
Autores principales: | Naoe, Yoshinori, Setoguchi, Ruka, Akiyama, Kaori, Muroi, Sawako, Kuroda, Masahiko, Hatam, Farah, Littman, Dan R., Taniuchi, Ichiro |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118685/ https://www.ncbi.nlm.nih.gov/pubmed/17646405 http://dx.doi.org/10.1084/jem.20062456 |
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