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Organ-dependent in vivo priming of naive CD4(+),but not CD8(+),T cells by plasmacytoid dendritic cells
Plasmacytoid dendritic cells (PDCs) play a pivotal role as cytokine-secreting accessory cells in the antimicrobial immune defense. In contrast, the capacity of PDCs to act as antigen-presenting cells in naive T cell priming remains unclear. By studying T cell responses in mice that lack conventional...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118686/ https://www.ncbi.nlm.nih.gov/pubmed/17646404 http://dx.doi.org/10.1084/jem.20062373 |