Cargando…
Mutations of the Igβ gene cause agammaglobulinemia in man
Agammaglobulinemia is a rare primary immunodeficiency characterized by an early block of B cell development in the bone marrow, resulting in the absence of peripheral B cells and low/absent immunoglobulin serum levels. So far, mutations in Btk, μ heavy chain, surrogate light chain, Igα, and B cell l...
| Autores principales: | , , , , , , , , , , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2007
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118692/ https://www.ncbi.nlm.nih.gov/pubmed/17709424 http://dx.doi.org/10.1084/jem.20070264 |