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An antigen-specific pathway for CD8 T cells across the blood-brain barrier

CD8 T cells are nature's foremost defense in encephalitis and brain tumors. Antigen-specific CD8 T cells need to enter the brain to exert their beneficial effects. On the other hand, traffic of CD8 T cells specific for neural antigen may trigger autoimmune diseases like multiple sclerosis. T ce...

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Detalles Bibliográficos
Autores principales: Galea, Ian, Bernardes-Silva, Martine, Forse, Penny A., van Rooijen, Nico, Liblau, Roland S., Perry, V. Hugh
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118703/
https://www.ncbi.nlm.nih.gov/pubmed/17682068
http://dx.doi.org/10.1084/jem.20070064