Hierarchy of Notch–Delta interactions promoting T cell lineage commitment and maturation

Notch1 (N1) receptor signaling is essential and sufficient for T cell development, and recently developed in vitro culture systems point to members of the Delta family as being the physiological N1 ligands. We explored the ability of Delta1 (DL1) and DL4 to induce T cell lineage commitment and/or ma...

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Detalles Bibliográficos
Autores principales: Besseyrias, Valerie, Fiorini, Emma, Strobl, Lothar J., Zimber-Strobl, Ursula, Dumortier, Alexis, Koch, Ute, Arcangeli, Marie-Laure, Ezine, Sophie, MacDonald, H. Robson, Radtke, Freddy
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118717/
https://www.ncbi.nlm.nih.gov/pubmed/17261636
http://dx.doi.org/10.1084/jem.20061442

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118717/
https://www.ncbi.nlm.nih.gov/pubmed/17261636
http://dx.doi.org/10.1084/jem.20061442

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