Cargando…

Expression of the transcription factor cKrox in peripheral CD8 T cells reveals substantial postthymic plasticity in CD4-CD8 lineage differentiation

Most T cells belong to either of two lineages defined by the mutually exclusive expression of CD4 and CD8 coreceptors: CD4 T cells are major histocompatibility complex (MHC) II restricted and have helper function, whereas CD8 T cells are MHC I restricted and have cytotoxic function. The divergence b...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jenkinson, S. Rhiannon, Intlekofer, Andrew M., Sun, Guangping, Feigenbaum, Lionel, Reiner, Steven L., Bosselut, Rémy
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2007
Materias:	Brief Definitive Reports
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118724/ https://www.ncbi.nlm.nih.gov/pubmed/17296789 http://dx.doi.org/10.1084/jem.20061982

Ejemplares similares

Requirement for T-bet in the aberrant differentiation of unhelped memory CD8(+) T cells
por: Intlekofer, Andrew M., et al.
Publicado: (2007)

Restricting Zap70 Expression to CD4(+)CD8(+) Thymocytes Reveals a T Cell Receptor–dependent Proofreading Mechanism Controlling the Completion of Positive Selection
por: Liu, Xiaolong, et al.
Publicado: (2003)

Thymic and Postthymic Regulation of Naïve CD4(+) T-Cell Lineage Fates in Humans and Mice Models
por: Belizário, José E., et al.
Publicado: (2016)

CD8β Increases CD8 Coreceptor Function and Participation in TCR–Ligand Binding
por: Renard, Valery, et al.
Publicado: (1996)

Lineage-specific Requirement for Signal Transducer and Activator of Transcription (Stat)4 in Interferon γ Production from CD4(+) Versus CD8(+) T Cells
por: Carter, Laura L., et al.
Publicado: (1999)

Quantitative Contribution of CD4 and CD8 to T Cell Antigen Receptor Serial Triggering
por: Viola, Antonella, et al.
Publicado: (1997)

Development of Cd8α/α and Cd8α/β T Cells in Major Histocompatibility Complex Class I–Deficient Mice
por: Das, Gobardhan, et al.
Publicado: (1999)

Restoration of CD28 Expression in CD28(−) CD8(+) Memory Effector T Cells Reconstitutes Antigen-induced IL-2 Production
por: Topp, Max S., et al.
Publicado: (2003)

CD40-deficient, Influenza-specific CD8 Memory T Cells Develop and Function Normally in a CD40-sufficient Environment
por: Lee, Byung O., et al.
Publicado: (2003)

Role of CD8 in Aberrant Function of Cytotoxic T Lymphocytes
por: Kessler, Benedikt, et al.
Publicado: (1997)

Asynchronous Coreceptor Downregulation after Positive Thymic Selection: Prolonged Maintenance of the Double Positive State in CD8 Lineage Differentiation Due to Sustained Biosynthesis of the CD4 Coreceptor
por: Barthlott, Thomas, et al.
Publicado: (1997)

Productive Infection of Neonatal CD8(+) T Lymphocytes by HIV-1
por: Yang, Liang Peng, et al.
Publicado: (1998)

Conversion of the CD8 lineage to CD4 T cells
por: Guzman, Maria P., et al.
Publicado: (2015)

CRTAM controls residency of gut CD4(+)CD8(+) T cells in the steady state and maintenance of gut CD4(+) Th17 during parasitic infection
por: Cortez, Victor S., et al.
Publicado: (2014)

Dependence on Bcl6 and Blimp1 drive distinct differentiation of murine memory and follicular helper CD4(+) T cells
por: Ciucci, Thomas, et al.
Publicado: (2021)

The clone size of peripheral CD8 T cells is regulated by TCR promiscuity
por: Hao, Yi, et al.
Publicado: (2006)

Estimating the Precursor Frequency of Naive Antigen-specific CD8 T Cells
por: Blattman, Joseph N., et al.
Publicado: (2002)

CD4(+) T Cell Help Impairs CD8(+) T Cell Deletion Induced by Cross-presentation of Self-Antigens and Favors Autoimmunity
por: Kurts, Christian, et al.
Publicado: (1997)

Niche-specific MHC II and PD-L1 regulate CD4(+)CD8αα(+) intraepithelial lymphocyte differentiation
por: Moon, Sookjin, et al.
Publicado: (2021)

Unraveling a Revealing Paradox: Why Major Histocompatibility Complex I–signaled Thymocytes “Paradoxically” Appear as CD4(+)8(lo) Transitional Cells During Positive Selection of CD8(+) T Cells
por: Bosselut, Remy, et al.
Publicado: (2003)

CD4/CD8 lineage commitment: back to instruction?
Publicado: (1996)

MHC Class II Expression Restricted to CD8α(+) and CD11b(+) Dendritic Cells Is Sufficient for Control of Leishmania major
por: Lemos, Maria P., et al.
Publicado: (2004)

An antigen-specific pathway for CD8 T cells across the blood-brain barrier
por: Galea, Ian, et al.
Publicado: (2007)

Oligoclonal Expansions of CD8(+) T Cells in Chronic HIV Infection Are Antigen Specific
por: Wilson, Jamie D.K., et al.
Publicado: (1998)

VEGF-A modulates expression of inhibitory checkpoints on CD8(+) T cells in tumors
por: Voron, Thibault, et al.
Publicado: (2015)

HDAC3 restrains CD8-lineage genes to maintain a bi-potential state in CD4(+)CD8(+) thymocytes for CD4-lineage commitment
por: Philips, Rachael Laura, et al.
Publicado: (2019)

Unique Chemotactic Response Profile and Specific Expression of Chemokine Receptors Ccr4 and Ccr8 by Cd4(+)Cd25(+) Regulatory T Cells
por: Iellem, Andrea, et al.
Publicado: (2001)

The Peripheral Deletion of Autoreactive CD8(+) T Cells Induced by Cross-presentation of Self-antigens Involves Signaling through CD95 (Fas, Apo-1)
por: Kurts, Christian, et al.
Publicado: (1998)

Cd8 Expression up to the Double-Positive CD3(Low/Intermediate) Stage of Thymic Differentiation Is Sufficient for Development of Peripheral Functional Cytotoxic T Lymphocytes
por: Zhang, X.-L., et al.
Publicado: (2001)

SARS-CoV-2 breakthrough infection in vaccinees induces virus-specific nasal-resident CD8(+) and CD4(+) T cells of broad specificity
por: Lim, Joey Ming Er, et al.
Publicado: (2022)

Association of the Adaptor Molecule Lat with Cd4 and Cd8 Coreceptors Identifies a New Coreceptor Function in T Cell Receptor Signal Transduction
por: Bosselut, Rémy, et al.
Publicado: (1999)

B cell survival, surface BCR and BAFFR expression, CD74 metabolism, and CD8(−) dendritic cells require the intramembrane endopeptidase SPPL2A
por: Bergmann, Hannes, et al.
Publicado: (2013)

Interleukin 12–dependent Interferon γ Production by CD8α(+)Lymphoid Dendritic Cells
por: Ohteki, Toshiaki, et al.
Publicado: (1999)

Interferon-γ acts directly on CD8(+) T cells to increase their abundance during virus infection
por: Whitmire, Jason K., et al.
Publicado: (2005)

GPR18 is required for a normal CD8αα intestinal intraepithelial lymphocyte compartment
por: Wang, Xiaoming, et al.
Publicado: (2014)

Bromodomain protein BRD4 directs and sustains CD8 T cell differentiation during infection
por: Milner, J. Justin, et al.
Publicado: (2021)

CD8(+) T cell depletion prevents neuropathology in a mouse model of globoid cell leukodystrophy
por: Sutter, Pearl A., et al.
Publicado: (2023)

Heritable Gene Regulation in the CD4:CD8 T Cell Lineage Choice
por: Issuree, Priya D. A., et al.
Publicado: (2017)

The transcription factor Ets1 is important for CD4 repression and Runx3 up-regulation during CD8 T cell differentiation in the thymus
por: Zamisch, Monica, et al.
Publicado: (2009)

Cytotoxic T Lymphocyte–associated Antigen 4 (CTLA-4) Can Regulate Dendritic Cell–induced Activation and Cytotoxicity of CD8(+) T Cells Independently of CD4(+)T Cell Help
por: McCoy, Kathy D., et al.
Publicado: (1999)

Cannot write session to /tmp/vufind_sessions/sess_bpstt7jdblngr59srebe5m8vgd