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Activation of the D prostanoid 1 receptor suppresses asthma by modulation of lung dendritic cell function and induction of regulatory T cells
Prostaglandins (PGs) can enhance or suppress inflammation by acting on different receptors expressed by hematopoietic and nonhematopoietic cells. Prostaglandin D(2) binds to the D prostanoid (DP)1 and DP2 receptor and is seen as a critical mediator of asthma causing vasodilation, bronchoconstriction...
Autores principales: | Hammad, Hamida, Kool, Mirjam, Soullié, Thomas, Narumiya, Shuh, Trottein, François, Hoogsteden, Henk C., Lambrecht, Bart N. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118726/ https://www.ncbi.nlm.nih.gov/pubmed/17283205 http://dx.doi.org/10.1084/jem.20061196 |
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