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A conserved surface on Toll-like receptor 5 recognizes bacterial flagellin

The molecular basis for Toll-like receptor (TLR) recognition of microbial ligands is unknown. We demonstrate that mouse and human TLR5 discriminate between different flagellins, and we use this difference to map the flagellin recognition site on TLR5 to 228 amino acids of the extracellular domain. T...

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Detalles Bibliográficos
Autores principales:	Andersen-Nissen, Erica, Smith, Kelly D., Bonneau, Richard, Strong, Roland K., Aderem, Alan
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2007
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118731/ https://www.ncbi.nlm.nih.gov/pubmed/17283206 http://dx.doi.org/10.1084/jem.20061400

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