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Conventional T-bet(+)Foxp3(−) Th1 cells are the major source of host-protective regulatory IL-10 during intracellular protozoan infection
Although interferon γ (IFN-γ) secretion is essential for control of most intracellular pathogens, host survival often also depends on the expression of interleukin 10 (IL-10), a cytokine known to counteract IFN-γ effector functions. We analyzed the source of regulatory IL-10 in mice infected with th...
Autores principales: | Jankovic, Dragana, Kullberg, Marika C., Feng, Carl G., Goldszmid, Romina S., Collazo, Carmen M., Wilson, Mark, Wynn, Thomas A., Kamanaka, Masahito, Flavell, Richard A., Sher, Alan |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118735/ https://www.ncbi.nlm.nih.gov/pubmed/17283209 http://dx.doi.org/10.1084/jem.20062175 |
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