Cargando…

Structure of the gene coding for the alpha polypeptide chain of the human complement component C4b-binding protein

The human gene coding for the 70-kD polypeptide of the complement regulatory component C4b-binding protein (C4BP alpha) spans over 40 kb of DNA and is composed of twelve exons. Upon transcription in liver, or in Hep-G2 cells, this gene produces a single transcript of 2,262 nucleotides, excepting the...

Descripción completa

Detalles Bibliográficos
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 1991
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118859/ https://www.ncbi.nlm.nih.gov/pubmed/2022920

Ejemplares similares

The membrane attack mechanism of complement: the three polypeptide chain structure of the eigth component (C8)
Publicado: (1976)

FOURTH COMPONENT OF HUMAN COMPLEMENT: DESCRIPTION OF A THREE POLYPEPTIDE CHAIN STRUCTURE
por: Schreiber, Robert D., et al.
Publicado: (1974)

Fully-sialylated alpha-chain of complement 4-binding protein: Diagnostic utility for ovarian clear cell carcinoma
por: Mikami, Mikio, et al.
Publicado: (2015)

Human Pentraxin 3 Binds to the Complement Regulator C4b-Binding Protein
por: Braunschweig, Anne, et al.
Publicado: (2011)

Antagonism of the complement component C4 by flavivirus nonstructural protein NS1
por: Avirutnan, Panisadee, et al.
Publicado: (2010)

Yersinia enterocolitica Serum Resistance Proteins YadA and Ail Bind the Complement Regulator C4b-Binding Protein
por: Kirjavainen, Vesa, et al.
Publicado: (2008)

THE ANTIGENIC STRUCTURE OF THE POLYPEPTIDE CHAINS OF HUMAN γ-GLOBULIN
por: Olins, D. E., et al.
Publicado: (1962)

C4b-binding protein binds to necrotic cells and DNA, limiting DNA release and inhibiting complement activation
por: Trouw, Leendert A., et al.
Publicado: (2005)

Complement component 1q subcomponent binding protein in the brain of the rat
por: Barna, János, et al.
Publicado: (2019)

Recruitment of C4b-binding protein is not a complement evasion strategy employed by Staphylococcus aureus
por: Li, Shuxian, et al.
Publicado: (2023)

Functional Recruitment of Human Complement Inhibitor C4b-Binding Protein to Outer Membrane Protein Rck of Salmonella
por: Ho, Derek K., et al.
Publicado: (2011)

Hijacking the human complement inhibitor C4b-binding protein by the sporozoite stage of the Plasmodium falciparum parasite
por: Khattab, Ayman, et al.
Publicado: (2022)

Structure of Vps4 with circular peptides and implications for translocation of two polypeptide chains by AAA+ ATPases
por: Han, Han, et al.
Publicado: (2019)

Editorial: Emerging Proteins and Polypeptides Expressed by “Non-Coding RNAs”
por: Liu, Wanting, et al.
Publicado: (2022)

The FK506 binding protein 13 kDa (FKBP13) interacts with the C-chain of complement C1q
por: Neye, Holger, et al.
Publicado: (2004)

Propagation of Fibrillar Structural Forms in Proteins Stopped by Naturally Occurring Short Polypeptide Chain Fragments
por: Roterman, Irena, et al.
Publicado: (2017)

Structure of the poly-C9 component of the complement membrane attack complex
por: Dudkina, Natalya V., et al.
Publicado: (2016)

Complement Component C3 Binds to the A3 Domain of von Willebrand Factor
por: Nolasco, Jennifer G., et al.
Publicado: (2018)

Structure-Guided Engineering of a Complement Component C3-Binding Nanobody Improves Specificity and Adds Cofactor Activity
por: Pedersen, Henrik, et al.
Publicado: (2022)

Hepatitis C Virus NS3/4A Protease Inhibits Complement Activation by Cleaving Complement Component 4
por: Mawatari, Seiichi, et al.
Publicado: (2013)

Association Study of the Complement Component C4 Gene in Tardive Dyskinesia
por: Zai, Clement C., et al.
Publicado: (2019)

Unexpected role of complement component 8 gamma chain in the inflamed brain
por: Kim, Jong-Heon, et al.
Publicado: (2023)

Neisseria gonorrhoeae co-opts C4b-binding protein to enhance complement-independent survival from neutrophils
por: Werner, Lacie M., et al.
Publicado: (2023)

Complement Activation-Independent Attenuation of SARS-CoV-2 Infection by C1q and C4b-Binding Protein
por: Beirag, Nazar, et al.
Publicado: (2023)

Expression of C5a-like biological activities by the fifth component of human complement (C5) upon limited digestion with noncomplement enzymes without release of polypeptide fragments
Publicado: (1983)

Chimeric Proteins Containing MAP-1 and Functional Domains of C4b-Binding Protein Reveal Strong Complement Inhibitory Capacities
por: Hertz, Cecilie E., et al.
Publicado: (2018)

High-throughput complement component 4 genomic sequence analysis with C4Investigator
por: Marin, Wesley M., et al.
Publicado: (2023)

MafB is a critical regulator of complement component C1q
por: Tran, Mai Thi Nhu, et al.
Publicado: (2017)

ANTIGENICITY OF POLYPEPTIDES (POLY ALPHA AMINO ACIDS) : XV. STUDIES ON THE IMMUNOGENICITY OF SYNTHETIC POLYPEPTIDES IN MICE
por: Pinchuck, Paul, et al.
Publicado: (1965)

Shiga Toxin 2a Binds to Complement Components C3b and C5 and Upregulates Their Gene Expression in Human Cell Lines
por: Kellnerová, Sára, et al.
Publicado: (2020)

Species-specific differences in the structure of orthopoxvirus complement-binding protein
por: Uvarova, Elena A, et al.
Publicado: (2001)

NMR solution structure and function of the C-terminal domain of eukaryotic class 1 polypeptide chain release factor
por: Mantsyzov, Alexey B, et al.
Publicado: (2010)

Biogenesis of membrane-bound and secreted immunoglobulins. II. Two forms of the human alpha chain translated in vitro and processed in vivo as distinct polypeptide chains
Publicado: (1981)

RECOMBINATION OF ANTIBODY POLYPEPTIDE CHAINS IN THE PRESENCE OF ANTIGEN
por: Metzger, Henry, et al.
Publicado: (1964)

Birth, life and death of nascent polypeptide chains
por: Jha, Sujata, et al.
Publicado: (2011)

Genetic Association of the Porcine C9 Complement Component with Hemolytic Complement Activity
por: Khoa, D. V. A., et al.
Publicado: (2015)

Complement component C4 structural variation and quantitative traits contribute to sex-biased vulnerability in systemic sclerosis
por: Kerick, Martin, et al.
Publicado: (2022)

Investigation of Complement Component C4 Copy Number Variation in Human Longevity
por: Flachsbart, Friederike, et al.
Publicado: (2014)

Structural and Functional Characterization of a Single-Chain Form of the Recognition Domain of Complement Protein C1q
por: Moreau, Christophe, et al.
Publicado: (2016)

Effects of Protein Structure on Iron–Polypeptide Vibrational Dynamic Coupling in Cytochrome c
por: Galinato, Mary Grace I., et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_31gqkhmpp3jafn8r6a3ouqsks4