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Functional analysis of the antigen binding site on the T cell receptor alpha chain
We have identified residues on a T cell receptor (TCR) alpha chain that are important for interaction with antigen/major histocompatibility complex (MHC). Using site-directed mutagenesis, we modified DNA encoding the postulated antigen/MHC binding loops on the TCR alpha chain expressed by the T cell...
Formato: | Texto |
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Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1992
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2119229/ https://www.ncbi.nlm.nih.gov/pubmed/1588281 |